Martin G. et al., in a study on Chinese hamster ovarian cancer cells (CHO), demonstrated that ABCC6 is not only able to mediate the efflux of glutathione conjugate but is also involved in resistance to some natural anti-cancer drugs, like doxorubicin, etoposide, actinomycin D, daunorubicin, and cisplatin [27]. The gene discussed is ABCC6; the disease is cancer.