ABCC6 and acute myeloid leukemia: However, the expression of ABCC6 and ABCB1 was found to be up-regulated after the treatment with Trichostatin A (an inhibitor of histone deacetylase) and 5-Aza-2′deoxycytidine (an inhibitor of DNA methyltransferase) in AML cell line HL-60.