Other biomarkers that came close but did not cross 0.75 area under the curve (AUC) threshold for AKI persistence were: urine CHI3L1, plasma cystine-C, urine NGAL, plasma proenkephalin, urine L-FABP and Nephrocheck biomarkers (TIMP-2 and IGFBP7). This evidence concerns the gene TIMP2 and acute kidney injury.