MACC1 and colorectal carcinoma: Indeed, considered separately, the combination of the three targets CEACAM5, ITGA6 and MACC1 selected to predict AA provided 75% and 79% sensitivity (for 95% specificity) for AA and CRC, respectively and the two targets S100A4 and PTGS2 selected to improve CRC detection provided 29% and 80% sensitivity (for 95% specificity) for AA and CRC prediction, respectively, suggesting that using distinct repertoires of targets for AA and CRC could be used to improve patient stratification for colonoscopy.