As shown in Figure 1, the median copy numbers for the transcripts of the first group which included GADD45B, ITGA2, MYBL2, MYC, PTGS2 and S100A4 were found to be significantly increased in the stools of patients with CRC as compared with the controls, while only three, including CEACAM5, ITGA6 and MACC1, were found to be over-represented also in patients with AA. The gene discussed is PTGS2; the disease is colorectal carcinoma.