The SW1353 cell line was reported to be activated by IL-1β and contributed to an increase in the expression of catabolic factors involved in the development of OA and RA, including pro-inflammatory cytokines, TNF-α, IL-6, and IL-8, and a cartilage-degrading enzyme, MMP-13 [29]. Here, CXCL8 is linked to rheumatoid arthritis.