Figure 4 shows the TIS of CEA, EpCAM, αvβ6, and uPAR in the diagnostic biopsy compared to the tumor bed in the corresponding resection specimen for each patient. CEA and EpCAM expression were significantly higher in the biopsies than in the tumor bed of the corresponding resection specimens (p < 0.01 for CEA and EpCAM). αvβ6 and uPAR expression was not significantly higher in the biopsies (respectively p = 0.082 and p = 0.246). This evidence concerns the gene CEACAM5 and neoplasm.