This may resemble earlier work on cutaneous melanoma cell lines that demonstrated mixed responses to YAP/TAZ inhibition: whereas reduced cell growth and reduced YAP/TAZ protein levels were reported after VP,35,39 inhibiting YAP/TAZ in cutaneous melanoma cell lines via shRNA, demonstrated no effect on proliferation in vitro.40 The gene discussed is TAFAZZIN; the disease is cutaneous melanoma.