MAPK8 and Hepatic cysts: Remarkably, we could not detect a significant difference in epithelial cell proliferation between JNK1/2LPC-KO, JNK1/2/RIPK1LPC-KO, and JNK1/2/RIPK1/Casp-8LPC-KO mice, arguing against a direct RIPK1-dependent modulation of biliary cell proliferation as the reason for liver cyst development in JNK1/2LPC-KO mice.