STC2 and cancer: In addition, STC2 plays an important role in the development of cancers (Esseghir et al. 2007; Ieta et al. 2009; Meyer et al. 2009; Tamura et al. 2009; Law and Wong 2010; Kita et al. 2011; Wu et al. 2017; He et al. 2019; Ke et al. 2019), including hepatocellular carcinoma, head and neck squamous cell carcinoma, lung cancer, laryngeal squamous cell carcinoma, breast cancer, and ovarian cancer.