To generate more data on the potential prognostic role of PD-L1 expression in kidney cancer and its relationship with intratumoral lymphocytes, a cohort of 1476 RCC—all treated in the pre-immunotherapy era—was analyzed in a tissue microarray format (TMA) for PD-L1 expression on tumor cells and immune cells by IHC. The gene discussed is CD274; the disease is neoplasm.