Using different cut-off levels to define positivity in tumor cells, PD-L1 positivity was detected at comparable frequencies of 12.9% (≥ 1% positive cells), 12.9% (≥ 5% positive cells), 11.0% (≥ 10% positive cells), and 4.9% (≥ 50% positive cells) in renal tumors. Here, CD274 is linked to kidney neoplasm.