BCL2L1 and acute myeloid leukemia: Combination therapy with azacitidine and ABT-737, an inhibitor of BCL2, BCLXL, and BCLW, not only displayed synergistic killing of AML cells but also decreased tissue invasion of leukemic cells in vivo, thus dampening a potential niche microenvironment-based evasion mechanism of resistance in AML[164].