Recently, Zhao et al. also found that MSCs transfected with a recombinant plasmid IL10-PEGFP-C1 were able to suppress the pancreatic cancer cell proliferation in vitro and to reduce the growth of tumor xenograft in vivo, prolonging the mouse survival, inhibiting tumor angiogenesis and reducing blood levels of TNF-α and IL-6 in mice with tumors (Zhao et al., 2020). This evidence concerns the gene TNF and neoplasm.