Presence of NLRP1, NLRP3, and AIM2 together with elevated IL-1β, IL-18, and IL-33 could be detected in the brain of ZIKV-infected patients with microcephaly (de Sousa et al., 2018a; de Sousa et al., 2018b). The gene discussed is NLRP1; the disease is microcephaly.