MYCN and neuroblastoma: These cell lines were chosen because of their relative expression of both MYCN and IGF2BP1, with SK-N-AS expressing minimal levels of either proteins and representing low-risk neuroblastoma, SK-N-BE(2) expressing moderate levels and representing intermediate-risk neuroblastoma, and SK-N-DZ expressing high levels and representing high risk neuroblastoma (Supplementary Figure S1).