AQP7 and type 2 diabetes mellitus: Higher expression of AQP7 was observed in obese insulin-resistant mice and adipose tissues of type 2 diabetic rats compared to their control groups, suggesting that dysregulation of AQP7 might be associated with increased input of glycerol for hepatic gluconeogenesis and increased glucose level in type 2 diabetes (Kishida et al., 2000; Lee et al., 2005; Rojek et al., 2008).