IL1F10 and dermatitis: IL-38 knockout mice treated with Aldara (5% IMQ) on their back skin showed a delayed resolution of skin inflammation (135), while IL-38-deficiency had no impact on the development or the resolution of skin inflammation in mice treated on their ears and no significant differences in mRNA expression of pro-inflammatory mediators were detected in ears of IL-38-deficient, as compared to WT mice after Aldara (5% IMQ) treatment (118).