C-reactive protein in general, has been used particularly in the fields of cardiovascular disease and autoimmune conditions as well as sepsis to indicate levels of inflammation, however over the last decade, its monomeric form (mCRP) has been highlighted as the major biologically active form, and both circulating levels of CRP as well as tissue-associated mCRP within the brain have been shown to be associated with development of dementia (10). This evidence concerns the gene CRP and Autoimmunity.