CHIT1 and infection: At day 5 (the experimental endpoint due to 20% weight loss in WT mice) after infection with C. albicans, Chit1−/− mice showed minimal weight loss by day 5 post infection compared to WT (Figure 2A), 92.3 ± 6.9 vs. 81.5 ± 4.8 %, P < 0.05).