Exosomes have been demonstrated to deliver human CFTR mature glycoprotein, as well as CFTR mRNA, in both Chinese hamster ovarian cells (Gonzalez et al., 2012) and CFTR-deficient cells derived from CF patients (Vituret et al., 2016; Villamizar et al., 2019). This evidence concerns the gene CFTR and cystic fibrosis.