MBP and Dravet syndrome: Because forced overexpression led to faster OPC maturation (seen by MBP expression strength; Figure 7), yet defective myelination, complex patterns of hypomyelination in DS could be explained, with myelin markers MBP and MOG depicting non-significant differences in the expression in early periods of life, then being progressively downregulated in DS patients (Abraham et al., 2012; Olmos-Serrano et al., 2016).