We also analysed the TCGA data and found that the breast cancer patients with low frequencies of CD8+ T cells and high frequencies of platelets had much lower overall survival rates than patients with high frequencies of CD8+ T cells and low frequencies of platelets (HR = 2.511 (1.48–4.25), log-rank P = 0.00038, Fig. 5h, Table 3). This evidence concerns the gene CD8A and breast cancer.