Similarly, the overall survival of breast cancer patients with low frequencies of CD8+ T cells and high frequencies of MDSCs had lower survival compared to patients with high frequencies of CD8+ T cells and low frequencies of MDSCs (log-rank test, HR = 3.37 (1.88–6.05), P < 0.0001 (Supplementary Fig. S6b). The gene discussed is CD8A; the disease is breast carcinoma.