F5 and non-small cell lung carcinoma: Among the 20 genes differentially expressed in blood sampled within both 2 or 3 years prior to diagnosis in metastatic cases, F5, TLR5 and C19orf59 have been previously observed differently expressed in whole blood of non-small cell lung cancer (NSCLC) patients compared to controls44 in one study and SLC25A5 in another study of blood samples from NSCLC cases and controls45.