In univariate analysis, miR-532-5p and miR-99b-3p were found to be the significant factors for BCR (HR: 2.01 [95% CI 1.13–3.58] and 1.87 [1.06–3.29], respectively), while age, pre-operative PSA, Gleason grade, margin status, PIN, and miR-26a-5p expression were not. This evidence concerns the gene BCR and prostate intraepithelial neoplasia.