BNIP3 and nasopharyngeal carcinoma: To determine the influence of BNIP3 mediated by LMP1 on NPC cell proliferation, the MTS results showed that the proliferation ability of LMP1-positive NPC cells was stronger than that of LMP1-negative NPC cells, but the proliferation ability of CM and HM cells with knockdown of BNIP3 showed no obvious change compared to the control group (Fig. 4A).