For example, ANX7 (n = 21,761) and PTSD6 (n = 9,537) GWASs have relatively little power as reflected in the larger standard errors in genetic correlations with these disorders, but nonetheless the strongest associations with these disorders were with components that match symptoms of the disorders (both correlated strongest with IC3, reflecting anxiety/depression/mental distress). The gene discussed is ANXA7; the disease is major depressive disorder.