High expression CCL18 was tightly related to poor prognosis in various tumor, including ovarian cancer [26], pancreatic ductal adenocarcinoma [27] gallbladder carcinoma [28] and gastric cancer [29] etc. Additionally, CCL18 was expressed not only in cells of the immune system, but also in tumor cells. This evidence concerns the gene CCL18 and gallbladder carcinoma.