Participants with T2D exhibited significantly higher BMI (24.6 kg/m2 vs. 23.9 kg/m2), FBG level (8.95 mmol/L vs. 5.36 mmol/L), TC (5.79 mmol/L vs. 5.58 mmol/L), TG (1.92 mmol/L vs. 1.58 mmol/L), ApoB (1.29 g/L vs. 1.14 g/L), and ApoB/A1 ratio (1.88 vs. 1.08) and lower HDL-C (1.24 mmol/L vs. 1.34 mmol/L) and ApoA1 (0.85 g/L vs. 1.21 g/L) compared to non-diabetic participants (all p < 0.05). The gene discussed is APOA1; the disease is type 2 diabetes mellitus.