VEGFA and rectal cancer: In patients with rectal cancer, George et al. studied 31 patients and found a positive correlation between serum VEGF and MR-derivedKtrans [23], Atkin et al. evaluated 15 patients and demonstrated a positive correlation between serum VEGF and IHC microvascular density (MVD) [24], and Yeo et al. analyzed 46 patients and demonstrated a positive correlation between IHC MVD and MR-derivedkep [25].