Although previous candidate gene studies of cervical cancer have explored regions related to immune function, cell cycle control, DNA repair, and other carcinogenic processes and identified genetic associations including CTLA4, FANCA, OAS3, SULF1, IFNG, DUT, DMC1, GTF2H4 and EVER1/2,19ERAP1, LMP7 and TAP2, TP53, TERT, IL10,20 and IL17 and TNF,21 these findings have not been replicated in larger cohorts. The gene discussed is PSMB8; the disease is cervical cancer.