CD40 and asthma: Herein we used wild-type (w.t.)and CD40-/- DC10 to assess the role of CD40 in DC10 reversal of the asthma phenotype in OVA-asthmatic mice, complementing IL-10 expression in the CD40-/- DC to assess whether IL-10 supplementation can over-ride a lack of CD40 signaling in these cells.