The CD40-/- DC had no significant impact of airway IL-5, IL-9 or IL-13 recall responses to allergen challenge (p>0.05 versus saline-treated asthmatic animals), although they did modestly reduce AHR, and airway eosinophilia and IL-4 (in each case, ≈60% attenuated activity relative to w.t. DC10; Fig 2A, 2B and 2C). Here, IL13 is linked to Increased total eosinophil count.