POT1 and hypothyroidism: Concomitantly to this work, a study by Labadie et al. (2020) confirmed the pleiotropic effect of these canine cancer loci by identifying a shared region for canine T zone lymphoma, mast cell tumors, and hypothyroidism in golden retriever; one of these loci on CFA14 that is involved in mast cell tumors and canine T zone lymphoma is ~800 kb downstream of POT1 locus identified in this study [54].