CLN5 and juvenile neuronal ceroid lipofuscinosis: Furthermore, several other miR prediction tools predicted miR-138-5p to target CLN5. Although miR-138 is regarded as a potential molecular regulator of human memory function [29], without further experimental validation, it would be futile to extrapolate if miR-138-mediated moderation of CLN5 contributes to impaired brain function in CLN5 Batten disease.