Moreover, univariate and multivariate Cox regression analyses suggested that YTHDF1 expression and lymph node metastasis were independent prognostic factors of poor survival in patients with GC from the GSE29272 dataset, while pathological stage and age were independent prognostic factors in TCGA cohort (Table 2 and Supplementary Tables S2, S4). The gene discussed is YTHDF1; the disease is metastatic malignant neoplasm in the lymph nodes.