METTL3 and neoplasm: Recent studies have revealed m6A methylation components can act as tumor-associated factors, including “writers” (METTL3/14, WTAP and KIAA1429), “erasers” (FTO and ALKBH5), and “readers” (YTHDF1/2/3, HNRNPA2B1, BCDIN3D) (Lin et al., 2016; Ma et al., 2017; Liu J. et al., 2018; Chen et al., 2019).