Up-expression of YTHDF1 was significantly associated with N stage (TCGA cohort, P = 0.019), cancer lesion (GEO cohort, P = 0.002), and tumor size (TMA1, P = 0.015) in patients with GC (Table 1 and Supplementary Tables S1, S3). The gene discussed is YTHDF1; the disease is gastric cancer.