The area under the ROC curve (AUC), cutoff value, sensitivity, and specificity of YTHDF1 were 0.52, 10.16, 97.9, and 8.2%, respectively, in TCGA cohort (Supplementary Figure S1C), indicating that YTHDF1 was a promising clinical marker in GC patients. This evidence concerns the gene YTHDF1 and gastric cancer.