Based on the OS datasets downloaded from Therapeutically Applicable Research to Generate Effective Treatments (TARGET), the Gene Set “ONDER CDH1 TARGETS 3 DN,” which involves genes downregulated in cancer cells after loss of function of E-cadherin, was positively correlated with LRH-1 expression using Gene Set Enrichment Analysis (GSEA) (Figure 4B). The gene discussed is CDH1; the disease is cancer.