Protein aggregation in the brain is often associated with neurodegenerative diseases, with α-synuclein (aSyn) aggregation being a pathogenic hallmark of Parkinson’s disease (Baba et al., 1998), and amyloid-beta (Aβ) and tau playing a role in the development of Alzheimer’s disease (Irvine et al., 2008). This evidence concerns the gene MAPT and neurodegenerative disease.