IL18 and acute kidney injury: The Translational Research Investigating Biomarker End Points in AKI (TRIBE-AKI) consortium found that urinary neutrophil gelatinase-associated lipocalin (NGAL) and urinary interleukin-18 (IL-18) concentrations rose acutely postoperatively in children with AKI but then decreased by the 5-year follow-up (25).