F2 and primary biliary cholangitis: White blood cell (WBC, RR = 1.072, 95% CI: 1.016–1.130, P=0.011), platelet counts (PLT, RR = 0.995, 95% CI: 0.992–0.998, P=0.003), and prothrombin time and international normalized ratio (PT/INR, RR = 1.799, 95% CI: 1.010–3.206, P=0.046) were independent prognostic factors in patients with PBC.