The absolute WBC counts (4.63 × 109/L versus 3.22 × 109/L, P=0.013), the levels of HDL-cholesterol (1.08 mmol/L versus 1.02 mmol/L, P=0.015), serum ALB (34.80 g/L versus 33.30 g/L, P=0.008), serum Ca2+ (2.18 mmol/L versus 2.15 mmol/L, P=0.004), and serum Hb (114.60 g/L versus 112.90 g/L, P=0.003) were found to be significantly lower in patients of the PBC-SS group compared with that of those with PBC alone (P < 0.05). Here, ALB is linked to primary biliary cholangitis.