Other polymorphisms with effects on COVID-19 progression were also observed in non-coding sequences for cathepsin L, monocyte chemoattractant protein-1 (CCL2), and neutrophil elastase genes, enhancing virus infection and inflammation (Ghafouri-Fard et al., 2020; Vargas-Alarcón et al., 2020). This evidence concerns the gene CTSL and COVID-19.