Here, mutations in the Fanconi Anemia pathway (p = 0.0024, Wilcoxon Test, Figure 4D), the IL-7 signaling pathway (p = 0.041, Wilcoxon Test, Figure 4D) and the AKT pathway (p = 0.018, Wilcoxon Test, Figure 4D) showed the strongest associations with a TIP [inflamed (tumor, CD4): Fanconi Anemia pathway, inflamed (tumor, CD8): IL-7 signaling pathway, AKT pathway]. This evidence concerns the gene CD8A and Fanconi anemia.