There was an association between inflamed (tumor, CD8) and the sign of cytotoxic and TH1 immune signature's effect size (Cytotoxic cells: p = 0.00012, Figure 3A, TH1: p = 1.4e-06, Figure 3C) and between inflamed (tumor, CD4) and the effect size of the TH17 signature (p = 0.007, Figure 3E). Here, CD4 is linked to neoplasm.