Genetic and epigenetic PCa-specific biomarkers in urine such as non-coding RNA of prostate cancer antigen-3 (PCA3), gene methylation of glutathione S-transferase P (GSTP1), and fusion transcripts for transmembrane protease serine-2 and ERG (TMPRSS2:ERG) have been developed and evaluated for the past decades (3). This evidence concerns the gene TMPRSS2 and posterior cortical atrophy.