The qPCR results showed that transfection of the CagA plasmid increased the expression of CagA and decreased miR-125b-5p, and transfection of miR-125b-5p increased the expression of miR-125b-5p, but it was still lower than that of the CagA negative control and did not affect the expression of CagA in either the DLD-1 or SW620 colon cancer cell lines (Figures 2(a) and 2(c)). Here, S100A8 is linked to malignant colon neoplasm.