CD47 and neoplasm: In addition, tailored antibody screening and engineering was used when later anti-CD47 monoclonal antibodies were developed, such as Lemzoparlimab (TJC4), SRF231, and AO-176 (65–67), in which candidates causing hemagglutination or red blood cell (RBC) phagocytosis were pre-excluded alongside the characterization and ranking of their anti-tumor activity.