APOE and heart disorder: Carrying the APOE ε4 allele was not significantly associated with MMSE score after adjusting for age, sex, education, and TOMM40 in model 1 (β: 0.41, 95% CI: −0.62 to 1.44, p = 0.44), and the results were similar when depressive symptoms and heart disease were additionally controlled for in model 2 (β: 0.47, 95% CI: −0.55 to 1.50, p = 0.36).