Importantly, the behavioral and biological defects in MAP6 KO mice are partially alleviated by long-term treatment with the gold-standard pharmacological treatments for psychiatric disorders, i.e., antipsychotics and antidepressants (Andrieux et al., 2002; Bégou et al., 2008; Delotterie et al., 2010; Fournet et al., 2012). This evidence concerns the gene MAP6 and psychiatric disorder.