In addition, and interestingly for this study, as an indication that cytoskeletal modulation might help alleviate neuronal defects related to psychiatric disorders, the MT modulators epothilone D (a Taxol-like component) and Davunetide (a peptide derived from the Activity Dependent Neuroprotective Protein, ADNP), were also shown to alleviate behavioral and biological defects in MAP6 KO mice, particularly those linked to synaptic impairments (Andrieux et al., 2006; Merenlender-Wagner et al., 2010; Fournet et al., 2012; Merenlender-Wagner et al., 2014). This evidence concerns the gene ADNP and psychiatric disorder.