At multivariate analysis, only TERT promoter mutations (odds ratio [OR] 8.7997; 95% confidence interval [CI] 1.9877–38.9567), age (OR: 1.0420; 95% CI 1.0023–1.0814), lymph node involvement (OR 4.2993; 95% CI 1.2530–14.7517), FTC histology (OR 1.6232; 95% CI 0.381–7.7926), and distant metastases (OR 40.3925; 95% CI 13.5846–120.1033) emerged as independent factors for a poor prognosis (p < 0.01) (Table 3). The gene discussed is TERT; the disease is thyroid cancer, nonmedullary, 2.