EGFR and cancer: TGFb-SMAD pathway (p = 0.001), endocytosis (p = 0.001), ErbB signalling pathway (p = 0.01) and ECM-receptor interaction pathway (p = 0.01) was regulated by the upmiRs and MAPK signalling (p = 0.001), PI3K-Akt signalling pathway (p = 0.001), pathways in Cancer (p = 0.001) and Wnt signalling pathways (p = 0.004) involved the downmiRs.