A 2D t-distributed stochastic neighbour embedding (tSNE) map (Fig. 1c, d) revealed clear separation into three phenotypic ‘territories’ reminiscent of the main breast cancer subtypes: Luminal (MCF7, CAMA-1, T47D and ZR-75-1), Her2-enriched (SK-BR-3) and Basal-like (MDA-MB-231 and MDA-MB-468) (Fig. 1c, d and Supplementary Fig. 1b). The gene discussed is ERBB2; the disease is breast carcinoma.