In addition, a recent phase III clinical trial (TULIP 2, NCT02446899) with a human monoclonal antibody (Anifrolumab) that specifically blocks IFNAR1 (type I interferon receptor subunit 1) meet the primary end-points and thus this new therapeutic approach promises to change the standard of care for SLE patients55. Here, IFNAR1 is linked to systemic lupus erythematosus.