CD4 and tuberculosis: The cfDNA concentration had a moderate inverse correlation with CD4 count (−0.43 [95% CI: −0.68 to −0.10; P = 0.011]) (Fig. 2A) and days to culture positivity (−0.36 [95% CI: −0.64 to −0.0060; P = 0.041]) (Fig. S1), but no significant correlation with days of anti-TB treatment (1 to 3 days), AFB smear score, or Alere urine LAM score (Table S3).