In a mouse model of breast cancer, scientists found that IR markedly enhanced the secretion of C-X-C motif chemokine ligand 16 (CXCL-16), which binds to C-X-C motif chemokine receptor (CXCR6) on Th1 cells and activates CD8+ T cells. This evidence concerns the gene CXCL16 and breast carcinoma.