PCSK9 and neoplasm: Univariate analysis showed that OS was associated with serum AFP levels (p = 0.001), tumor size (p < 0.001), tumor cell differentiation (p = 0.008), microvascular invasion (p = 0.018) and PCSK9 expression (p = 0.035) (Table 2, Fig. 1b); DFS was associated with serum AFP levels (p = 0.005), number of tumors (p = 0.037), tumor size (p = 0.002), and PCSK9 expression (p = 0.007) (Table 2, Fig. 1c).